Address
1275 York Avenue
Box 207
City, State, ZIP
New York, NY 10021
Phone
(212) 639-2354
Research field
Molecular Biology
Award year
1996

Research

The Koff laboratory currently has efforts in 3 areas: 1) The interactions of p27 with other proteins: specifically, are the Cip-Kips redundant in regulating growth arrest in differentiating cells? And how do they interact with the pocket-proteins? 2) The development of a mouse model that mimics the prognostic significance of p27 in human disease.3) The regulation of p27.