Eros Lazzerini Denchi, Ph.D. | The Pew Charitable Trusts

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标题: Stadtman Investigator
Department: Laboratory of Genome Integrity
机构: National Cancer Institute, National Institutes of Health
Address: 37 Convent Dr, Bild 37, 2144B
City, State, ZIP: Bethesda, MD 20892
Phone: (240) 760-7031
电子邮件: [email protected]
Website: https://irp.nih.gov/pi/eros-lazzerini-denchi
Research field: Stem Cell Biology
获奖年份: 2011

Research

In our laboratory, we study the mechanisms by which DNA damage results in premature aging, with a focus on telomeric DNA damage. Damage to telomeres is particularly relevant for aging since it accumulates throughout the human lifespan, contributing to telomere dysfunction which is believed to be one of the underlying causes of aging-associated pathologies. Our goal is to identify the key physiological processes that lead to aging upon telomeric DNA damage-findings that will significantly impact public health and could reveal novel therapeutic approaches to aging.

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