Thomas Schwartz
Address
77 Massachusetts Avenue Room 68-480
City, State, ZIP
Cambridge, MA 2139
Phone
(617) 452-3851
Award year
2007

Research

Research in our lab aims at understanding protein function on the basis of atomic structure determination using X-ray crystallography as an important tool. Our focal point is the elucidation of the structure and function of the Nuclear Pore Complex (NPC), the gateway into and out of the cell's nucleus and thus of central importance for separating transcription and translation. We employ an integrative approach to this research area combining structure determination with biochemical, biophysical, cell biological and genetic methods.