Eros Lazzerini Denchi, Ph.D. | The Pew Charitable Trusts

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Trust Article

Título: Stadtman Investigator
Departamento: Laboratory of Genome Integrity
Institución: National Cancer Institute, National Institutes of Health
Dirección: 37 Convent Dr, Bild 37, 2144B
Ciudad, Estado, Código postal: Bethesda, MD 20892
Número de teléfono: (240) 760-7031
Correo electrónico: [email protected]
Sitio: https://irp.nih.gov/pi/eros-lazzerini-denchi
Campo de investigación: Stem Cell Biology
Año del premio: 2011

Research

In our laboratory, we study the mechanisms by which DNA damage results in premature aging, with a focus on telomeric DNA damage. Damage to telomeres is particularly relevant for aging since it accumulates throughout the human lifespan, contributing to telomere dysfunction which is believed to be one of the underlying causes of aging-associated pathologies. Our goal is to identify the key physiological processes that lead to aging upon telomeric DNA damage-findings that will significantly impact public health and could reveal novel therapeutic approaches to aging.

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