Carlos G. Osorio, M.D., Ph.D.

Research

Cholera is characterized by a severe watery diarrhea caused by toxigenic Vibrio cholerae, which is a curved rod gram-negative and highly motile bacterium. This disease is endemic in southern Asia and parts of Africa and Latin America, where seasonal outbreaks occur widely and are particularly associated with poverty and poor sanitation. Research in my lab is focused on the genetic characterization of pathogenicity islands, genomic islands acquired by horizontal gene transfer, in Vibrio parahaemolyticus. In addition we are investigating the specific vrulence factros, VOA 1321, 1327 and 1380 of Vibrio parahaemolyticus expressed in vivo during an infection.