Franck Polleux, Ph.D. | The Pew Charitable Trusts

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Título: Professor
Departamento: Department of Neuroscience
Institución: Columbia University, Mortimer B. Zuckerman Mind Brain Behavior Institute, Kavli Institute for Brain Science
Dirección: Jerome L. Greene Science Center
3227 Broadway, L-5-050, MC 9853
Ciudad, Estado, Código postal: New York, NY 10027
Número de teléfono: (212) 342-4413
Correo electrónico: [email protected]
Sitio: https://www.polleuxlab.zi.columbia.edu/
Campo de investigación: Neuroscience
Año del premio: 2005

Research

Our lab is studying the developmental mechanisms patterning connections in the cerebral cortex. We are specifically interested in identifying the signaling pathways controlling three important and inter-related aspects of cortical neurons differentiation: migration, axon pathfinding and dendritic differentiation. In order to analyze the role of specific signaling pathways in the specification of cortical connectivity, we are combining a wide array of molecular and cellular approaches such as: (1) biochemistry and proteomics, (2) time-lapse confocal microscopy, (3) calcium-imaging, (4) ex vivo and in utero electroporation, (5) in vitro co-culture assays and (6) analysis of mice presenting targeted gene deletion or promoter-driven GFP expressing mice.

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