Karin M. Hoffmeister, M.D.

Departamento
Medicine/Hematology
Dirección
Karp Family Research Building 6th Floor
1 Blackfan Circle
Ciudad, Estado, Código postal
Boston, MA 02115
Número de teléfono
(617) 355-9010
Correo electrónico
[email protected]
Campo de investigación
Immunology
Año del premio
2005

Research

We characterize Golgi glycosyltransferase enzymes expressed in platelets, their possible extracellular targets and their delivery mechanism(s) from megakaryocytes to platelets. We also investigate the role of extracellular platelet glycan remodeling in platelet survival, function and interaction between platelets and/or with other blood cells. We also study platelet clearance mechanisms, with focus on carbohydrate-lectin mediated platelet clearance.