Peter M. Tessier, Ph.D.

Research

The Tessier lab is investigating fundamental aspects of protein misfolding and aggregation related to three classes of proteins (prions, amyloids and antibodies). We combine protein engineering with a variety of cutting-edge biochemical and biophysical methods to understand the molecular underpinnings of misfolding and aggregation processes. We aim to elucidate how protein misfolding can be prevented, reversed or redirected with the long-term goal of developing new therapeutic candidates to treat disease, and improving the selection and formulation of aggregation-resistant antibodies.